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Journal article

Impact of intended and relative dose intensity of R‐CHOP in a large, consecutive cohort of elderly diffuse large B‐cell lymphoma patients treated with curative intent: no difference in cumulative incidence of relapse comparing patients by age

Abstract:

Background

The increasing incidence of diffuse large B‐cell lymphoma (DLBCL) in ageing populations places a significant burden on healthcare systems. Co‐morbidity, frailty, and reduced organ and physiological reserve contribute to treatment‐related complications. The optimal dose intensity of R‐CHOP to optimize outcome across different ages with variable frailty and comorbidity burden is unclear.

Objectives and Methods

We examined the...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/joim.12889

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
ORCID:
0000-0001-5095-6367
Publisher:
Wiley
Journal:
Journal of Internal Medicine More from this journal
Volume:
285
Issue:
6
Pages:
681-692
Publication date:
2019-04-11
Acceptance date:
2019-02-27
DOI:
EISSN:
1365-2796
ISSN:
0954-6820
Pmid:
30811713
Language:
English
Keywords:
Pubs id:
pubs:978361
UUID:
uuid:d0981953-4663-4286-9d59-8b21ef1ffbb2
Local pid:
pubs:978361
Source identifiers:
978361
Deposit date:
2019-03-29

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