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Journal article

Structural insights into how 5-hydroxymethylation influences transcription factor binding.

Abstract:
Transcription factor binding and high resolution crystallographic studies (1.3 Å) of Dickerson-Drew duplexes with cytosine, methylcytosine and hydroxymethylcytosine bases provide evidence that C-5 cytosine modifications could regulate transcription by context dependent effects on DNA transcription factor interactions.
Publication status:
Published

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Publisher copy:
10.1039/c3cc48151d

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Journal:
Chemical Communications More from this journal
Volume:
50
Issue:
15
Pages:
1794-1796
Publication date:
2014-02-01
DOI:
EISSN:
1364-548X
ISSN:
1359-7345
Language:
English
Pubs id:
pubs:440306
UUID:
uuid:d073f998-988e-4d1b-a5e9-382c981ae01b
Local pid:
pubs:440306
Source identifiers:
440306
Deposit date:
2013-12-12

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