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The expression of hybrid HIV:Ty virus-like particles in yeast.

Abstract:

The yeast retrotransposon, Ty, encodes a set of proteins that are assembled into virus-like particles, Ty-VLPs (refs 1, 2). These proteins include Ty-VLP structural proteins, a protease that mediates cleavage of primary translation products and a reverse transcriptase. The major structural components of Ty-VLPs are proteolytic products of the primary translation product, p1 (ref. 3). We have recently shown that protein p1 alone can form Ty-VLPs (ref. 3). Here we demonstrate that p1 fusion pro...

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Publication status:
Published

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Publisher copy:
10.1038/329068a0

Authors


Dawson, KM More by this author
More by this author
Institution:
University of Oxford
Department:
Oxford, MSD, Pathology Dunn School
Kingsman, SM More by this author
Kingsman, AJ More by this author
Journal:
Nature
Volume:
329
Issue:
6134
Pages:
68-70
Publication date:
1987
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
URN:
uuid:d02080e6-93dd-4895-a9c7-1e49ce9869ea
Source identifiers:
13893
Local pid:
pubs:13893

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