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Mathematical modelling of corneal epithelium wound healing

Abstract:

We propose a reaction-diffusion model of the mechanisms involved in the healing of corneal surface wounds. The model focuses on the stimulus for increased mitotic and migratory activity, specifically the role of epidermal growth factor. Analysis of the model equations elucidates the interaction and roles of the model parameters in determining the speed of healing and the shape of the traveling wave solutions which correspond to the migration of cells into the wound during the initial phase of...

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P. D. Dale More by this author
P. K. Maini More by this author
J. A. Sherratt More by this author
Publication date:
1994
URN:
uuid:cffaecaa-e54a-46fc-bc29-c68faf297fd9
Local pid:
oai:eprints.maths.ox.ac.uk:493

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