- Abstract:
-
Aichi virus (AiV), an unusual and poorly characterized picornavirus, classified in the genus Kobuvirus, can cause severe gastroenteritis and deaths in children below the age of five years, especially in developing countries1,2. The seroprevalence of AiV is approximately 60% in children under the age of ten years and reaches 90% later in life3,4. There is no available vaccine or effective antiviral treatment. Here, we describe the structure of AiV at 3.7 Å. This first high-resolution structure...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Accepted Manuscript
- Files:
-
-
(pdf, 12.6mb)
-
- Publisher copy:
- 10.1038/nmicrobiol.2016.150
-
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- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Microbiology Journal website
- Volume:
- 1
- Pages:
- 16150
- Publication date:
- 2016-09-05
- Acceptance date:
- 2016-07-21
- DOI:
- ISSN:
-
2058-5276
- Pubs id:
-
pubs:641710
- URN:
-
uri:cff9ca7d-90b1-48de-a794-db2258ec066a
- UUID:
-
uuid:cff9ca7d-90b1-48de-a794-db2258ec066a
- Local pid:
- pubs:641710
- Copyright holder:
- Macmillan Publishers Limited
- Copyright date:
- 2016
- Notes:
- © 2016 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. This is the accepted manuscript version of the article. The final version is available online from Nature Microbiology at: https://doi.org/10.1038/nmicrobiol.2016.150
Journal article
Structure of human Aichi virus and implications for receptor binding
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