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Journal article

Active inter-cellular forces in collective cell motility

Abstract:

The collective behaviour of confluent cell sheets is strongly influenced both by polar forces, arising through cytoskeletal propulsion, and by active inter-cellular forces, which are mediated by interactions across cell-cell junctions. We use a phase-field model to explore the interplay between these two contributions and compare the dynamics of a cell sheet when the polarity of the cells aligns to (i) their main axis of elongation, (ii) their velocity and (iii) when the polarity direction ex...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1098/rsif.2020.0312

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Theoretical Physics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Theoretical Physics
Role:
Author
ORCID:
0000-0002-7483-8434
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Theoretical Physics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Physics
Sub department:
Theoretical Physics
Role:
Author
ORCID:
0000-0001-8268-5469
Publisher:
The Royal Society Publisher's website
Journal:
Journal of the Royal Society Interface Journal website
Volume:
17
Issue:
169
Pages:
20200312
Publication date:
2020-08-12
Acceptance date:
2020-07-20
DOI:
EISSN:
1742-5662
ISSN:
1742-5689
Pmid:
32781933
Language:
English
Keywords:
Pubs id:
1126449
Local pid:
pubs:1126449
Deposit date:
2020-08-19

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