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Journal article

A polymorphism in human CD1A is associated with susceptibility to tuberculosis.

Abstract:

CD1 proteins are antigen-presenting molecules that evolved to present lipids rather than peptides to T cells. However, unlike major histocompatibility complex genes, CD1 genes show low rates of polymorphism and have not been clearly associated with human disease. We report that an intronic polymorphism in CD1A (rs411089) is associated with susceptibility to tuberculosis in two cohorts of Vietnamese adults (combined cohort odds ratio 1.78; 95% confidence interval: 1.24-2.57; P=0.001). These da...

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Publication status:
Published

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Publisher copy:
10.1038/gene.2014.5

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Journal:
Genes and immunity More from this journal
Volume:
15
Issue:
3
Pages:
195-198
Publication date:
2014-01-01
DOI:
EISSN:
1476-5470
ISSN:
1466-4879
Language:
English
Keywords:
Pubs id:
pubs:447858
UUID:
uuid:cfa5f6dc-970e-4c53-a9f0-0d85eb1f16e2
Local pid:
pubs:447858
Source identifiers:
447858
Deposit date:
2014-05-10

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