- Abstract:
-
Vascular endothelial growth factor (VEGF) is a cytokine that is involved in tumor angiogenesis. Wild-type p53 (wt-p53) protein has been shown in cell lines to suppress angiogenesis through thrombospondin regulation. In this study, we immunohistochemically examined the expression of VEGF, nuclear and wild-type cytoplasmic p53, bcl-2, epidermal growth factor receptor, and c-erbB-2 oncoprotein; vascular grade; proliferation index; and extent of necrosis in non-small cell lung cancer (NSCLC). We ...
Expand abstract - Publication status:
- Published
- Journal:
- Clinical cancer research : an official journal of the American Association for Cancer Research
- Volume:
- 4
- Issue:
- 12
- Pages:
- 3017-3024
- Publication date:
- 1998-12-05
- ISSN:
-
1078-0432
- URN:
-
uuid:cf81ceda-302d-4936-8158-11fed444dbb1
- Source identifiers:
-
486710
- Local pid:
- pubs:486710
- Language:
- English
- Keywords:
- Copyright date:
- 1998
Journal article
Vascular endothelial growth factor, wild-type p53, and angiogenesis in early operable non-small cell lung cancer.
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