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Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms

Abstract:

Bacterial biofilms are a major and ongoing concern for public health, featuring both inherited genetic resistance traits and a conferred innate tolerance to traditional antibiotic therapies. Consequently, there is a growing need for novel methods of drug delivery, to increase the efficacy of antimicrobial agents. This research evaluated the anti-biofilm and bactericidal effects of ultrasound responsive gas-microbubbles (MBs) of either air or nitric oxide, using an in vitro Pseudomonas aerugin...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fcimb.2022.956808

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Role:
Author
ORCID:
0000-0002-3763-3106
Publisher:
Frontiers Media
Journal:
Frontiers in Cellular and Infection Microbiology More from this journal
Volume:
12
Article number:
956808
Publication date:
2022-08-04
Acceptance date:
2022-07-14
DOI:
EISSN:
2235-2988
Pmid:
35992170
Language:
English
Keywords:
Pubs id:
1275248
Local pid:
pubs:1275248
Deposit date:
2022-11-04

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