Journal article
Hologenomic adaptations underlying the evolution of sanguivory in the common vampire bat
- Abstract:
- Adaptation to specialized diets often requires modifications at both genomic and microbiome levels. We applied a hologenomic approach to the common vampire bat (Desmodus rotundus), one of the only three obligate blood-feeding (sanguivorous) mammals, to study the evolution of its complex dietary adaptation. Specifically, we assembled its high-quality reference genome (scaffold N50 = 26.9 Mb, contig N50 = 36.6 kb) and gut metagenome, and compared them against those of insectivorous, frugivorous and carnivorous bats. Our analyses showed a particular common vampire bat genomic landscape regarding integrated viral elements, a dietary and phylogenetic influence on gut microbiome taxonomic and functional profiles, and that both genetic elements harbour key traits related to the nutritional (for example, vitamin and lipid shortage) and non-nutritional (for example, nitrogen waste and osmotic homeostasis) challenges of sanguivory. These findings highlight the value of a holistic study of both the host and its microbiota when attempting to decipher adaptations underlying radical dietary lifestyles.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Preview, Version of record, pdf, 6.4MB, Terms of use)
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- Publisher copy:
- 10.1038/s41559-018-0476-8
Authors
- Publisher:
- Springer Nature
- Journal:
- Nature Ecology and Evolution More from this journal
- Volume:
- 2
- Pages:
- 659–668
- Publication date:
- 2018-02-19
- Acceptance date:
- 2018-01-11
- DOI:
- EISSN:
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2397-334X
- Pmid:
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29459707
- Language:
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English
- Keywords:
- Pubs id:
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pubs:826165
- UUID:
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uuid:cedc2093-981e-4e98-976b-0b9b8613d5ab
- Local pid:
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pubs:826165
- Source identifiers:
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826165
- Deposit date:
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2019-02-05
Terms of use
- Copyright holder:
- Macmillan Publishers Limited
- Copyright date:
- 2018
- Notes:
- © 2018 Macmillan Publishers Limited, part of Springer Nature. All rights reserved. Tis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. Te images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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