Neuroschistosomiasis.

Journal article

Schistosomiasis (bilharzia) is a neglected tropical disease caused by digenetic trematode platyhelminths of the genus Schistosoma. Neuroschistosomiasis is one of the most severe clinical outcomes associated with schistosome infection. Neurological complications early during the course of infection are thought to occur through in situ egg deposition following aberrant migration of adult worms to the brain or spinal cord. The presence of eggs in the CNS induces a cell-mediated Th2-driven periov...

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Authors: Ross, A; McManus, D; Farrar, J; Hunstman, R; Gray, D

• Publication status: Published
• Journal: Journal of neurology
• Volume: 259
• Issue: 1
• Pages: 22-32
• Publication date: 2012-01-01
• DOI: 10.1007/s00415-011-6133-7
• EISSN: 1432-1459
• ISSN: 0340-5354
• Language: English
• Keywords: Animals; Neuroschistosomiasis; Humans; Praziquantel; Schistosoma; Artemisinins; Life Cycle Stages; Tomography, X-Ray Computed; Magnetic Resonance Imaging; Immunologic Tests; Schistosomicides; Adrenal Cortex Hormones