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Common variation in the CD36 (fatty acid translocase) gene is associated with left-ventricular mass.

Abstract:

AIMS: Genetic variation in the fatty acid translocase (CD36) gene has been shown in animal models to affect several risk factors for the development of left-ventricular hypertrophy, but this phenotype has not, thus far, been investigated in humans. We examined the relationship between common genetic polymorphisms in the CD36 gene and left-ventricular mass. METHODS AND RESULTS: We studied a cohort of 255 families comprising 1425 individuals ascertained via a hypertensive proband. Seven single-...

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Publication status:
Published

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Authors


Mayosi, BM More by this author
Rahman, TJ More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Cardiovascular Medicine, BHF Centre of Research Excellence
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Journal:
Journal of hypertension
Volume:
29
Issue:
4
Pages:
690-695
Publication date:
2011-04-05
DOI:
EISSN:
1473-5598
ISSN:
0263-6352
URN:
uuid:ceb0b2c3-0f56-4580-a09f-35ec0a075ddc
Source identifiers:
120164
Local pid:
pubs:120164

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