Journal article
Multiply efficient trials: combining multiple trial arms and critical secondary questions increases trial efficiency
- Abstract:
-
Designing explanatory trials to answer additional questions such as how and for whom treatments work should be a priority for improving trial efficiency. Multiple arm trials are also more efficient, as they provide more information about treatments over a shorter time span [1]. We studied the benefits of multiple trial arms and explanatory design using the Pacing, Graded Activity, and Cognitive Behaviour Therapy: A Randomised Evaluation (PACE) trial as an example. This trial studied three com...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- BioMed Central Publisher's website
- Journal:
- 4th International Clinical Trials Methodology Conference (ICTMC 2017) Journal website
- Publication date:
- 2017-05-01
- Acceptance date:
- 2016-11-10
- DOI:
- ISSN:
-
1745-6215
Item Description
- Pubs id:
-
pubs:734960
- UUID:
-
uuid:ceac9018-35b2-4342-8527-2f963b18261a
- Local pid:
- pubs:734960
- Source identifiers:
-
734960
- Deposit date:
- 2017-11-01
Terms of use
- Copyright holder:
- Sharpe et al
- Copyright date:
- 2017
- Notes:
- © The Author(s). 2017 Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
- Licence:
- CC Attribution (CC BY)
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