Journal article
Modelling DNA origami self-assembly at the domain level
- Abstract:
-
We present a modelling framework, and basic model parameterization, for the study of DNA origami folding at the level of DNA domains. Our approach is explicitly kinetic and does not assume a specific folding pathway. The binding of each staple is associated with a free-energy change that depends on staple sequence, the possibility of coaxial stacking with neighbouring domains, and the entropic cost of constraining the scaffold by inserting staple crossovers. A rigorous thermodynamic model is ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
Actions
Authors
Funding
+ Royal Society
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Funding agency for:
Turberfield, AJ
Grant:
Wolfson Research Merit Award
+ European Research Council
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Funding agency for:
Dannenberg, F
Kwiatkowska, M
Grant:
VERIWARE
VERIWARE
+ Engineering and Physical Sciences Research Council
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Grant:
EP/G037930/1 and EP/P504287/1
Bibliographic Details
- Publisher:
- American Institute of Physics Publisher's website
- Journal:
- Journal of Chemical Physics Journal website
- Volume:
- 143
- Issue:
- 16
- Article number:
- 165102
- Publication date:
- 2015-10-28
- Acceptance date:
- 2015-10-07
- DOI:
- ISSN:
-
1089-7690
Item Description
- Language:
- English
- Pubs id:
-
pubs:572337
- UUID:
-
uuid:cdfc7812-1164-4ceb-bf60-936d49af93ee
- Local pid:
- pubs:572337
- Source identifiers:
-
572337
- Deposit date:
- 2015-11-12
Terms of use
- Copyright holder:
- AIP Publishing LLC
- Copyright date:
- 2015
- Rights statement:
- Copyright © 2015 AIP Publishing LLC
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