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Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface

Abstract:

Annexin A1 (ANXA1) has an important role in cell-cell communication in the host defense and neuroendocrine systems. In both systems, its actions are exerted extracellularly via membrane-bound receptors on adjacent sites after translocation of the protein from the cytoplasm to the cell surface of adjacent cells. This study used molecular, microscopic, and pharmacological approaches to explore the mechanisms underlying the cellular exportation of ANXA1 in TtT/GF (pituitary folliculo-stellate) c...

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Publisher copy:
10.1096/fj.05-5319fje

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Role:
Author
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Journal:
FASEB Journal
Volume:
20
Issue:
9
Pages:
1498-1500
Publication date:
2006-07-05
DOI:
EISSN:
1530-6860
ISSN:
0892-6638
URN:
uuid:cdfc48b4-f3a6-435c-9014-22ba51f953a1
Source identifiers:
115471
Local pid:
pubs:115471

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