Journal article
Protective effect of creatine elevation against ischaemia reperfusion injury is retained in the presence of co-morbidities and during cardioplegia.
- Abstract:
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Aims
Ischaemic heart disease is most prevalent in the ageing population and often exists with other comorbidities; however the majority of laboratory research uses young, healthy animal models. Several recent workshops and focus meetings have highlighted the importance of using clinically relevant models to help aid translation to realistic patient populations. We have previously shown that mice over-expressing the creatine transporter (CrT-OE) have elevated intracellular creatine...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 380.3KB)
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- Publisher copy:
- 10.1371/journal.pone.0146429
Authors
Funding
Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PloS One Journal website
- Volume:
- 11
- Issue:
- 1
- Pages:
- e0146429
- Publication date:
- 2016-01-01
- Acceptance date:
- 2015-12-15
- DOI:
- EISSN:
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1932-6203
- ISSN:
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1932-6203
Item Description
- Language:
- English
- Pubs id:
-
pubs:597848
- UUID:
-
uuid:cdec9e60-7058-4e29-bf30-54da586ecfaf
- Local pid:
- pubs:597848
- Source identifiers:
-
597848
- Deposit date:
- 2016-03-23
Terms of use
- Copyright holder:
- Whittington et al
- Copyright date:
- 2016
- Notes:
- © 2016 Whittington et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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