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Elevated Blood Pressure in Preterm-Born Offspring Associates With a Distinct Antiangiogenic State and Microvascular Abnormalities in Adult Life.

Abstract:

Preterm-born individuals have elevated blood pressure. We tested the hypothesis that this associates with an enhanced antiangiogenic circulating profile and that this association is mediated by variations in capillary density. We studied 204 adults aged 25 years (range, 20-30 years), of which 102 had been followed up prospectively since very preterm birth (mean gestational age, 30.3±2.5 weeks) and 102 were born term to uncomplicated pregnancies. A panel of circulating biomarkers, including so...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher:
American Heart Association Publisher's website
Journal:
Hypertension Journal website
Volume:
65
Issue:
3
Pages:
607-614
Publication date:
2014-12-05
DOI:
EISSN:
1524-4563
ISSN:
0194-911X
URN:
uuid:cd9d70c9-cdbb-4a06-96f8-e41fcc93ffa0
Source identifiers:
501622
Local pid:
pubs:501622

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