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Thesis

Determinants of medium-term blood pressure variability and the related risks of stroke and dementia

Abstract:

Visit-to-visit variability in blood pressure (BP) increases stroke risk, independent of mean BP. However, its physiological validity, the ideal method of measurement and the mechanisms increasing cardiovascular risk are unclear.

In meta-analyses of individual patient data, I pooled associations between BP variability and risk of stroke, all cardiovascular events and death. I then determined antihypertensive drug-class differences in cardiovascular risk, intra-individual (I-VR) and i...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Research group:
Stroke Prevention Research Unit
Oxford college:
Wadham College
Role:
Author
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Division:
MSD
Department:
Clinical Neurosciences
Role:
Author

Contributors

Division:
MSD
Department:
Clinical Neurosciences
Role:
Supervisor
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Funding agency for:
Webb, A
Grant:
HMRTCA0
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:cd97daf5-c6d7-4386-94d7-a710d8ea5292
Local pid:
ora:9049
Deposit date:
2014-10-08

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