Journal article
Heart regeneration: beyond new muscle and vessels
- Abstract:
-
The most striking consequence of a heart attack is the loss of billions of heart muscle cells, alongside damage to the associated vasculature. The lost cardiovascular tissue is replaced by scar formation, which is non-functional and results in pathological remodelling of the heart and ultimately heart failure. It is, therefore, unsurprising that the heart regeneration field has centred efforts to generate new muscle and blood vessels through targeting cardiomyocyte proliferation and angiogene...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Cardiovascular Research Journal website
- Volume:
- 117
- Issue:
- 3
- Pages:
- 727–742
- Publication date:
- 2021-01-04
- Acceptance date:
- 2020-10-21
- DOI:
- EISSN:
-
1755-3245
- ISSN:
-
0008-6363
- Pmid:
-
33241843
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1149063
- Local pid:
- pubs:1149063
- Deposit date:
- 2021-01-19
Terms of use
- Copyright holder:
- Sayers and Riley.
- Copyright date:
- 2020
- Rights statement:
- © The Author(s) 2021. Published on behalf of the European Society of Cardiology. All rights reserved.
- Notes:
-
This is the accepted manuscript version of the article. The final version is available online from
Oxford University Press at: https://doi.org/10.1093/cvr/cvaa320
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