Journal article icon

Journal article

Heart regeneration: beyond new muscle and vessels

Abstract:

The most striking consequence of a heart attack is the loss of billions of heart muscle cells, alongside damage to the associated vasculature. The lost cardiovascular tissue is replaced by scar formation, which is non-functional and results in pathological remodelling of the heart and ultimately heart failure. It is, therefore, unsurprising that the heart regeneration field has centred efforts to generate new muscle and blood vessels through targeting cardiomyocyte proliferation and angiogene...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1093/cvr/cvaa320

Authors


More by this author
Institution:
University of Oxford
Role:
Author
Publisher:
Oxford University Press
Journal:
Cardiovascular Research More from this journal
Volume:
117
Issue:
3
Pages:
727–742
Publication date:
2021-01-04
Acceptance date:
2020-10-21
DOI:
EISSN:
1755-3245
ISSN:
0008-6363
Pmid:
33241843
Language:
English
Keywords:
Pubs id:
1149063
Local pid:
pubs:1149063
Deposit date:
2021-01-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP