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Accelerated long-term forgetting in presymptomatic autosomal dominant Alzheimer's disease: a cross-sectional study

Abstract:

Background

Tests sensitive to presymptomatic changes in Alzheimer’s disease could be valuable for clinical trials. Accelerated long-term forgetting—during which memory impairment becomes apparent over longer periods than usually assessed, despite normal performance on standard cognitive testing—has been identified in other temporal lobe disorders. We assessed whether accelerated long-term forgetting is a feature of presymptomatic autosomal dominant (familial) Alzheimer’s disease,...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1016/s1474-4422(17)30434-9

Authors


Weston, PSJ More by this author
Nicholas, JM More by this author
Henley, SMD More by this author
Macpherson, K More by this author
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Alzheimer’s Research UK More from this funder
National Institute for Health Research More from this funder
Dunhill Medical Trust More from this funder
Epilepsy Research UK More from this funder
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Publisher:
Elsevier Publisher's website
Journal:
Lancet Neurology Journal website
Volume:
17
Issue:
2
Pages:
123-132
Publication date:
2018-01-17
Acceptance date:
2017-11-14
DOI:
EISSN:
1474-4465
ISSN:
1474-4422
Pubs id:
pubs:823456
URN:
uri:ccf56c99-fb7a-4ecb-ab5f-80c9611cfb3e
UUID:
uuid:ccf56c99-fb7a-4ecb-ab5f-80c9611cfb3e
Local pid:
pubs:823456
Language:
English
Keywords:

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