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A genome-wide association study for regulators of micronucleus formation in mice

Abstract:

In mammals the regulation of genomic instability plays a key role in tumor suppression and also controls genome plasticity, which is important for recombination during the processes of immunity and meiosis. Most studies to identify regulators of genomic instability have been performed in cells in culture or in systems that report on gross rearrangements of the genome, yet subtle differences in the level of genomic instability can contribute to whole organism phenotypes such as tumor predispos...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1534/g3.116.030767

Authors


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Role:
Author
ORCID:
0000-0003-3277-7466
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Role:
Author
ORCID:
0000-0001-8134-9308
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Role:
Author
ORCID:
0000-0001-7496-2075
Publisher:
Oxford University Press
Journal:
G3: Genes | Genomes | Genetics More from this journal
Volume:
6
Issue:
8
Pages:
2343-2354
Place of publication:
England
Publication date:
2016-08-01
Acceptance date:
2016-05-24
DOI:
EISSN:
2160-1836
ISSN:
2160-1836
Pmid:
27233670

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