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Journal article : Review

Location, location, location: how the tissue microenvironment affects inflammation in RA

Abstract:

Current treatments for rheumatoid arthritis (RA) do not work well for a large proportion of patients, or at all in some individuals, and cannot cure or prevent this disease. One major obstacle to developing better drugs is a lack of complete understanding of how inflammatory joint disease arises and progresses. Emerging evidence indicates an important role for the tissue microenvironment in the pathogenesis of RA. Each tissue is made up of cells surrounded and supported by a unique extracellu...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41584-020-00570-2

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
ORCID:
0000-0001-6924-6402
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Author
Publisher:
Springer Nature
Journal:
Nature Reviews Rheumatology More from this journal
Volume:
17
Issue:
4
Pages:
195–212
Publication date:
2021-02-01
Acceptance date:
2020-12-21
DOI:
EISSN:
1759-4804
ISSN:
1759-4790
Language:
English
Keywords:
Subjects:
Subtype:
Review
Pubs id:
1137438
Local pid:
pubs:1137438
Deposit date:
2020-10-13

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