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Phenotype Algorithms for the Identification and Characterization of Vaccine-Induced Thrombotic Thrombocytopenia in Real World Data: A Multinational Network Cohort Study

Abstract:
Our findings suggest that identifying VITT in observational data presents a substantial challenge, as implementing VITT case definitions based on the co-occurrence of TWT results in large and heterogeneous incidence rate and in a cohort of patints with baseline characteristics that are inconsistent with the VITT cases reported to date.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s40264-022-01187-y

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Role:
Author
ORCID:
0000-0002-6976-2594
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Role:
Author
ORCID:
0000-0002-4949-7236
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Role:
Author
ORCID:
0000-0002-0651-0613
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Role:
Author
ORCID:
0000-0002-0847-6682
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Role:
Author
ORCID:
0000-0003-0362-6298


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Funder identifier:
10.13039/501100010767
Grant:
806968


Publisher:
Springer
Journal:
Drug Safety: The Official Journal of the International Society of Pharmacovigilance More from this journal
Volume:
45
Issue:
6
Pages:
685-698
Publication date:
2022-06-02
DOI:
EISSN:
1179-1942
ISSN:
0114-5916


Language:
English
Keywords:
Pubs id:
1262612
Local pid:
pubs:1262612
Source identifiers:
W4282936489
Deposit date:
2026-04-24
ARK identifier:
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