Journal article
Brain Pathology in Mucopolysaccharidoses (MPS) Patients with Neurological Forms
- Abstract:
-
Mucopolysaccharidoses (MPS) are the group of lysosomal storage disorders caused by deficiencies of enzymes involved in the stepwise degradation of glycosaminoglycans. To identify brain pathology common for neurological MPS, we conducted a comprehensive analysis of brain cortex tissues from post-mortem autopsy materials of eight patients affected with MPS I, II, IIIA, IIIC, and IIID, and age-matched controls. Frozen brain tissues were analyzed for the abundance of glycosaminoglycans (heparan, ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Bibliographic Details
- Publisher:
- MDPI Publisher's website
- Journal:
- Journal of Clinical Medicine Journal website
- Volume:
- 9
- Issue:
- 2
- Article number:
- 396
- Publication date:
- 2020-02-01
- Acceptance date:
- 2020-01-27
- DOI:
- EISSN:
-
2077-0383
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
1087144
- Local pid:
- pubs:1087144
- Deposit date:
- 2020-02-14
Terms of use
- Copyright holder:
- Viana et al.
- Copyright date:
- 2020
- Rights statement:
- © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
- Licence:
- CC Attribution (CC BY)
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