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Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.

Abstract:

BACKGROUND: Oxycodone is a strong opioid agonist used to treat severe pain. It is commonly combined with milder analgesics such as paracetamol. This review updates a previous review that concluded, based on limited data, that all doses of oxycodone exceeding 5 mg, with or without paracetamol, provided analgesia in postoperative pain, but with increased incidence of adverse events compared with placebo. Additional new studies provide more reliable estimates of efficacy and harm. OBJECTIVES: To...

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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
Journal:
Cochrane database of systematic reviews
Issue:
3
Pages:
CD002763
Publication date:
2009-01-01
DOI:
EISSN:
1469-493X
Source identifiers:
240886
Language:
English
Keywords:
Pubs id:
pubs:240886
UUID:
uuid:cb912eae-71d9-4c06-b056-67419edd3a8f
Local pid:
pubs:240886
Deposit date:
2013-11-16

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