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Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.

Abstract:

BACKGROUND: Oxycodone is a strong opioid agonist used to treat severe pain. It is commonly combined with milder analgesics such as paracetamol. This review updates a previous review that concluded, based on limited data, that all doses of oxycodone exceeding 5 mg, with or without paracetamol, provided analgesia in postoperative pain, but with increased incidence of adverse events compared with placebo. Additional new studies provide more reliable estimates of efficacy and harm. OBJECTIVES: To...

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Neuroscience
Role:
Author
Journal:
The Cochrane database of systematic reviews
Issue:
3
Pages:
CD002763
Publication date:
2009-01-01
DOI:
EISSN:
1469-493X
URN:
uuid:cb912eae-71d9-4c06-b056-67419edd3a8f
Source identifiers:
240886
Local pid:
pubs:240886

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