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Journal article

A hippocampus-accumbens tripartite neuronal motif guides appetitive memory in space

Abstract:

Retrieving and acting on memories of food-predicting environments are fundamental processes for animal survival. Hippocampal pyramidal cells (PYRs) of the mammalian brain provide mnemonic representations of space. Yet the substrates by which these hippocampal representations support memory-guided behavior remain unknown. Here, we uncover a direct connection from dorsal CA1 (dCA1) hippocampus to nucleus accumbens (NAc) that enables the behavioral manifestation of place-reward memories. By moni...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.cell.2018.12.037

Authors


More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pharmacology
Role:
Author
More from this funder
Name:
Wellcome Trust
Grant:
Investigator Award 101821 to P.J.M
More from this funder
Name:
Biotechnology and Biological Sciences Research Council
Grant:
BB/N0059TX/1 to D.D
More from this funder
Name:
Medical Research Council
Grant:
MC_UU_12024/1
Publisher:
Cell Press
Journal:
Cell More from this journal
Volume:
176
Issue:
6
Pages:
1393-1406
Publication date:
2019-02-14
Acceptance date:
2018-12-20
DOI:
ISSN:
0092-8674
Keywords:
Pubs id:
pubs:954399
UUID:
uuid:cb80f18d-b7da-4ba0-974a-89c5b4a690fd
Local pid:
pubs:954399
Deposit date:
2018-12-21

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