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In-vivo 31P-MRS of skeletal muscle and liver: A way for non-invasive assessment of their metabolism

Abstract:

In addition to direct assessment of high energy phosphorus containing metabolite content within tissues, phosphorus magnetic resonance spectroscopy (31P-MRS) provides options to measure phospholipid metabolites and cellular pH, as well as the kinetics of chemical reactions of energy metabolism in vivo. Even though the great potential of 31P-MR was recognized over 30 years ago, modern MR systems, as well as new, dedicated hardware and measurement techniques provide further opportunities for re...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.ab.2017.01.018

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Name:
Royal Society
Grant:
098436/Z/12/Z/
More from this funder
Name:
Wellcome Trust
Grant:
098436/Z/12/Z/
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Name:
APVV
Grant:
15-0029
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Name:
Slovak Grant Agencies VEGA
Grant:
2/0001/17/
More from this funder
Name:
OeNB Jubilaeumsfond
Grant:
15363
15455
Publisher:
Elsevier
Journal:
Analytical Biochemistry More from this journal
Volume:
529
Pages:
193–215
Publication date:
2017-01-21
Acceptance date:
2017-01-19
DOI:
EISSN:
1096-0309
ISSN:
0003-2697
Keywords:
Pubs id:
pubs:674976
UUID:
uuid:cb750154-ea9c-4c08-8fb1-5acdb2f1e90c
Local pid:
pubs:674976
Deposit date:
2017-01-31

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