Single dose antidepressant administration modulates the neural processing of self-referent personality trait words.

Journal article

Drugs which inhibit the re-uptake of monoamines in the brain are effective in the treatment of depression; however, the neuropsychological mechanisms which lead to the resolution of depressive symptomatology are unclear. Behavioral studies in healthy volunteers suggest that acute administration of the selective norepinephrine reuptake inhibitor reboxetine modulates emotional processing. The current study therefore explored the neural basis of this effect. A single dose of reboxetine (4 mg) or...

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Authors: Miskowiak, K; Papadatou-Pastou, M; Cowen, P; Goodwin, G; Norbury, R

• Publication status: Published
• Journal: NeuroImage
• Volume: 37
• Issue: 3
• Pages: 904-911
• Publication date: 2007-09-01
• DOI: 10.1016/j.neuroimage.2007.05.036
• EISSN: 1095-9572
• ISSN: 1053-8119
• Language: English
• Keywords: Brain; Self Concept; Self-Assessment; Antidepressive Agents; Magnetic Resonance Imaging; Female; Adult; Emotions; Task Performance and Analysis; Brain Mapping; Verbal Behavior; Personality; Morpholines; Male; Humans