Journal article icon

Journal article

Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

Abstract:

Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common ancestor with the gorilla parasite Plasmodium praefalciparum. Little is known about the other gorilla- and chimpanzee-infecting species in the same (Laverania) subgenus as P. falciparum, but none of them are capable of establishing repeated infection and transmission in humans. To elucidate underlying mechanisms and the evolutionary history of this subgenus, we have generated multiple genomes from all know...

Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

Actions


Access Document


Files:
Publisher copy:
10.1038/s41564-018-0162-2

Authors


More by this author
Role:
Author
ORCID:
0000-0002-1246-7404
More by this author
Role:
Author
ORCID:
0000-0003-0764-9171
More from this funder
Name:
Wellcome Trust
Funding agency for:
Newbold, C
Grant:
104792/Z/14/Z
WT 206194
More from this funder
Name:
Medical Research Council
Funding agency for:
Crellen, T
More from this funder
Name:
Institut de recherche pour le développement
More from this funder
Name:
Centre International de Recherches Médicales de Franceville
More from this funder
Name:
Centre national de la recherche scientifique
Publisher:
Nature Publishing Group
Journal:
Nature Microbiology More from this journal
Volume:
3
Issue:
6
Pages:
687–697
Publication date:
2018-05-21
Acceptance date:
2018-04-16
DOI:
ISSN:
2058-5276
Pmid:
29784978
Language:
English
Keywords:
Pubs id:
pubs:853904
UUID:
uuid:cb384063-915a-4c56-8a0d-aafc2cea5099
Local pid:
pubs:853904
Source identifiers:
853904
Deposit date:
2018-05-30

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP