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Genomes of all known members of a Plasmodium subgenus reveal paths to virulent human malaria

Abstract:

Plasmodium falciparum, the most virulent agent of human malaria, shares a recent common ancestor with the gorilla parasite Plasmodium praefalciparum. Little is known about the other gorilla- and chimpanzee-infecting species in the same (Laverania) subgenus as P. falciparum, but none of them are capable of establishing repeated infection and transmission in humans. To elucidate underlying mechanisms and the evolutionary history of this subgenus, we have generated multiple genomes from all know...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1038/s41564-018-0162-2

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Role:
Author
ORCID:
0000-0002-1246-7404
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Role:
Author
ORCID:
0000-0003-0764-9171
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Funding agency for:
Newbold, C
Agence Nationale de la Recherche More from this funder
Centre national de la recherche scientifique More from this funder
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Publisher:
Nature Publishing Group Publisher's website
Journal:
Nature Microbiology Journal website
Volume:
3
Issue:
6
Pages:
687–697
Publication date:
2018-05-21
Acceptance date:
2018-04-16
DOI:
ISSN:
2058-5276
Pubs id:
pubs:853904
URN:
uri:cb384063-915a-4c56-8a0d-aafc2cea5099
UUID:
uuid:cb384063-915a-4c56-8a0d-aafc2cea5099
Local pid:
pubs:853904
Language:
English
Keywords:

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