Synaptic transmission of hippocampal mossy fibres in health and disease

Thesis

Dentate microcircuitry is thought to be involved in filtering, integrating, and relaying extrinsic hippocampal inputs to the hippocampus proper, which contributes to memory formation and retrieval. The axons of granule cells are called mossy fibres (MFs), and contain multiple terminal types that form characteristic synaptic connections with their postsynaptic targets. This diversity of presynaptic release sites that exists on the same MF provides an extremely interesting axonal type to stu...

Expand abstract

Authors: Lalic, T

• Publication date: 2009
• Type of award: DPhil
• Level of award: Doctoral
• Awarding institution: University of Oxford
• Language: English
• Keywords: mossy fibres; Hippocampus; kainate receptors; in vitro electrophysiology
• Subjects: Neuroscience