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Lack of requirement for cell cooperation in the antibody response to DNP conjugated to levan.

Abstract:

The cellular basis of the antibody response to dinitrophenylated levan (DNP-LE) was investigated using a combination of in vivo and in vitro techniques. The results indicated that the induction of the primary response to DNP-LE is independent of the function of macrophages or T cells. However, these cells may regulate the response to DNP-LE (as for other T-independent antigens), as suggested by the prolongation of the response by adjuvants. No evidence of collaboration between carrier (LE)-re...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Cellular immunology
Volume:
16
Issue:
1
Pages:
106-114
Publication date:
1975-03-01
DOI:
EISSN:
1090-2163
ISSN:
0008-8749
Source identifiers:
481886

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