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CRF in the differential diagnosis of Cushing's syndrome: a comparison with the dexamethasone suppression test.

Abstract:

Accurate differential diagnosis of the precise cause of Cushing's syndrome can be difficult, and conventional tests such as those based on the use of dexamethasone may be misleading. We have therefore studied the cortisol and ACTH responses to ovine corticotrophin-releasing factor (CRF-41) in 28 consecutive patients with Cushing's syndrome, and compared the diagnostic value of this test with that of the high-dose dexamethasone suppression test (8 mg/day for 48 h). Of 20 patients with confirme...

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Publication status:
Published

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Journal:
Clinical endocrinology
Volume:
29
Issue:
2
Pages:
167-178
Publication date:
1988-08-05
DOI:
EISSN:
1365-2265
ISSN:
0300-0664
URN:
uuid:cacc602c-e464-40f8-a617-da3a370d78b5
Source identifiers:
138373
Local pid:
pubs:138373

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