A role for heterocellular coupling and EETs in dilation of rat cremaster arteries.

Journal article

OBJECTIVE: The authors probed endothelium-dependent dilation and endothelial cell Ca2+ handling in myogenically active resistance arteries. METHODS: First-order arteries were removed from rat cremaster muscles, cannulated, and pressurized (75 mmHg). Vessel diameter and endothelial cell Ca2+ were monitored using confocal microscopy, and arterial ultrastructure was determined using electron microscopy. RESULTS: Acetylcholine (ACh) stimulated elevations and oscillations in endothelial cell Ca2+...

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Authors: McSherry, I; Sandow, S; Campbell, W; Falck, JR; Hill, M

• Publication status: Published
• Journal: Microcirculation (New York, N.Y. : 1994)
• Volume: 13
• Issue: 2
• Pages: 119-130
• Publication date: 2006-03-01
• DOI: 10.1080/10739680500466400
• EISSN: 1549-8719
• ISSN: 1073-9688
• Language: English
• Keywords: Dose-Response Relationship, Drug; Calcium; Endothelium, Vascular; Vasodilator Agents; Calcium Signaling; Male; Vasodilation; Rats; Gap Junctions; Rats, Wistar; Potassium Channels, Calcium-Activated; Acetylcholine; Enzyme Inhibitors; Muscle, Smooth, Vascular; Animals; Sodium-Potassium-Exchanging ATPase; Arteries