Journal article
Recurrent genetic defects on chromosome 5q in myeloid neoplasms
- Abstract:
-
BACKGROUND: Deletion of chromosome 5q (del(5q)) is the most common karyotypic abnormality in myeloid neoplasms. MATERIALS AND METHODS: To define the pathogenic molecular features associated with del(5q), next-generation sequencing was applied to 133 patients with myeloid neoplasms (MDS; N = 69, MDS/MPN; N = 5, sAML; N = 29, pAML; N = 30) with del(5q) as a sole abnormally or a part of complex karyotype and results were compared to molecular features of patients diploid for chr5. FINDINGS: A nu...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
+ American Cancer Society
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Grant:
Research
Scholar Grant 123436-RSG-12-159-01-DMC (to TL
+ National Institutes of
Health
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Grant:
R01HL082983,U54RR019391
K24HL077522
toJPM,U54RR019391toMAS
Edward P. Evans Foundation
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AA & MDS International
Foundation
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Bibliographic Details
- Publisher:
- Impact Journals Publisher's website
- Journal:
- Oncotarget Journal website
- Volume:
- 8
- Issue:
- 4
- Pages:
- 6483-6495
- Publication date:
- 2016-12-23
- Acceptance date:
- 2016-12-16
- DOI:
- ISSN:
-
1949-2553
Item Description
Terms of use
- Copyright holder:
- Hosono et al
- Copyright date:
- 2016
- Notes:
- This article is licensed under a Creative Commons Attribution 3.0 License.
- Licence:
- CC Attribution (CC BY)
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