Services for people at high risk improve outcomes in patients with first episode psychosis

Journal article

OBJECTIVE: About one‐third of patients referred to services for people at high risk for psychosis may have already developed a first episode of psychosis (FEP). We compared clinical outcomes in FEP patients who presented to either high risk or conventional mental health services. METHOD: Retrospective study comparing duration of hospital admission, referral‐to‐diagnosis time, need for compulsory hospital admission and frequency of admission in patients with FEP who initially presented to a high‐risk service (n = 164) to patients with FEP who initially presented to conventional mental health services (n = 2779). Regression models were performed, controlling for several confounders. RESULTS: FEP patients who had presented to a high‐risk service spent 17 fewer days in hospital [95% CI: −33.7 to (−0.3)], had a shorter referral‐to‐diagnosis time [B coefficient −74.5 days, 95% CI: −101.9 to −(47.1)], a lower frequency of admission [IRR: 0.49 (95% CI: 0.39–0.61)] and a lower likelihood of compulsory admission [OR: 0.52 (95% CI: 0.34–0.81)] in the 24 months following referral, as compared to FEP patients who were first diagnosed at conventional services. CONCLUSION: Services for people at high risk for psychosis are associated with better clinical outcomes in patients who are already psychotic

Authors: Fusar-Poli, P; Díaz-Caneja, CM; Patel, R; Valmaggia, L; Byrne, M

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Wiley
• Journal: Acta Psychiatrica Scandinavica
• Volume: 133
• Issue: 1
• Pages: 76-85
• Publication date: 2015-09-11
• DOI: 10.1111/acps.12480
• EISSN: 1600-0447
• ISSN: 0001-690X
• Language: English
• Keywords: Pediatrics; Mental health service; Mental health; Family medicine; Retrospective cohort study; Psychiatry; Emergency medicine; Psychosis; Confounding; Referral; Internal medicine; Medicine; Hospital admission