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A non-synonymous variant in ADH1B is strongly associated with prenatal alcohol use in a European sample of pregnant women.

Abstract:

Pregnant women are advised to abstain from alcohol despite insufficient evidence on the fetal consequences of moderate prenatal alcohol use. Mendelian randomization could help distinguish causal effects from artifacts due to residual confounding and measurement errors; however, polymorphisms reliably associated with alcohol phenotypes are needed. We aimed to test whether alcohol dehydrogenase (ADH) gene variants were associated with alcohol use before and during pregnancy. Ten variants in fou...

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Publication status:
Published

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Publisher copy:
10.1093/hmg/ddp388

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
NPEU
Role:
Author
Journal:
Human molecular genetics More from this journal
Volume:
18
Issue:
22
Pages:
4457-4466
Publication date:
2009-11-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Language:
English
Keywords:
Pubs id:
pubs:30181
UUID:
uuid:ca5ee51a-375d-4a80-8e50-327ec35cc6d9
Local pid:
pubs:30181
Source identifiers:
30181
Deposit date:
2012-12-19

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