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Journal article

Central Nervous System Involvement by Novel Clade 2.3.2.1e H5N1 Avian Influenza Virus in a Pediatric Patient

Abstract:
Novel clade 2.3.2.1e A(H5N1) virus was detected in cerebrospinal fluid but not in respiratory, rectal swab, or blood samples of an 8-year-old boy presenting with meningoencephalitis without respiratory symptoms. Cerebrospinal fluid A(H5N1) hemagglutinin–specific antibody levels were higher than those of sera. Clinicians should be aware of emerging clade 2.3.2.1e A(H5N1)–associated meningoencephalitis.
Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/ofid/ofag283

Authors

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Role:
Author
ORCID:
0000-0003-2444-1786
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Institution:
University of Oxford
Role:
Author
ORCID:
0009-0004-4993-6616


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Funder identifier:
10.13039/100010269
Grant:
226120/Z/22/Z
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Funder identifier:
https://ror.org/001aqnf71
Grant:
UKRI1045
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Funder identifier:
https://ror.org/029chgv08


Publisher:
Oxford University Press
Journal:
Open Forum Infectious Diseases More from this journal
Volume:
13
Issue:
5
Pages:
ofag283
Article number:
ofag283
Publication date:
2026-05-07
Acceptance date:
2026-04-30
DOI:
EISSN:
2328-8957
ISSN:
2328-8957


Language:
English
Keywords:
Source identifiers:
4075089
Deposit date:
2026-05-23
ARK identifier:
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