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Journal article

Human newborn bacille Calmette–Guérin vaccination and risk of tuberculosis disease: a case-control study

Abstract:

Background

An incomplete understanding of the immunological mechanisms underlying protection against tuberculosis (TB) hampers the development of new vaccines against TB. We aimed to define host correlates of prospective risk of TB disease following bacille Calmette–Guérin (BCG) vaccination.

Methods

In this study, 5,726 infants vaccinated with BCG at birth were enrolled. Host responses in blood collected at 10 weeks of age were compare...

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Publication status:
Published
Peer review status:
Peer reviewed

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Authors


Contributors

Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Jenner Institute
Role:
Contributor
More from this funder
Name:
NIAID NIH HHS
Grant:
R01-AI065653
R01 AI065653
More from this funder
Name:
Department of Health
Grant:
NF-SI-0509-10233
NF-SI-0514-10158
More from this funder
Name:
Wellcome Trust
Grant:
84323
More from this funder
Name:
National Institute for Health Research
Grant:
NF-SI-0514-10158
NF-SI-0509-10233
Publisher:
BioMed Central
Journal:
BMC Medicine More from this journal
Volume:
14
Issue:
1
Pages:
76
Publication date:
2016-05-16
Acceptance date:
2016-04-23
DOI:
EISSN:
1741-7015
Pmid:
27183822
Language:
English
Keywords:
Pubs id:
pubs:708378
UUID:
uuid:ca024b02-1d1b-4e0b-a9d7-f935669fe3a7
Local pid:
pubs:708378
Source identifiers:
708378
Deposit date:
2019-07-03

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