Pyrexia, anaemia and acute renal failure secondary to omeprazole.

Journal article

We present the case of a 77-year-old woman who initially presented with pyrexia of unknown origin, anaemia and mild renal impairment. When her omeprazole was stopped she improved rapidly. When omeprazole was re-started she developed fever and acute renal failure, which again settled quickly on discontinuation of omeprazole. This case demonstrates how drugs can cause severe multisystem disorders that may appear to be infective or inflammatory.

Authors: Landray, M; Ringrose, T; Ferner, R; Arnold, I

• Publication status: Published
• Journal: Postgraduate medical journal
• Volume: 74
• Issue: 873
• Pages: 416-418
• Publication date: 1998-07-01
• DOI: 10.1136/pgmj.74.873.416
• EISSN: 1469-0756
• ISSN: 0032-5473
• Language: English
• Keywords: Humans; Fever; Recurrence; Blood Sedimentation; Anemia; Acute Kidney Injury; Anti-Inflammatory Agents; Prednisolone; Aged; Dyspepsia; Anti-Ulcer Agents; Omeprazole; Female