Conference item
Structural studies on the leukocyte co-stimulatory molecule, B7-1
- Abstract:
-
B7-1 and B7-2 are glycoproteins expressed on antigen presenting cells. The binding of these molecules to the T-cell homodimers, CD28 and CTLA-4, generate 'costimulatory' and inhibitory signals in T cells, respectively. The crystal structure of the extracellular region of B7-1 (sB7-1), solved to 3 Angstrom resolution, consists of a novel combination of two Ig-like domains, one characteristic of adhesion molecules and the other previously seen only in antigen receptors. In the crystal lattice, ...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- ACTIVATING AND INHIBITORY IMMUNOGLOBULIN-LIKE RECEPTORS
- Pages:
- 63-72
- Publication date:
- 2001-01-01
- Event title:
- CREST International Symposium on Immunoglobulin-like Receptors
- Source identifiers:
-
16010
- ISBN:
- 4431702970
Item Description
- Keywords:
- Pubs id:
-
pubs:16010
- UUID:
-
uuid:c9c2eebc-338e-4576-85c9-809f0e618c46
- Local pid:
- pubs:16010
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2001
If you are the owner of this record, you can report an update to it here: Report update to this record