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Recent applications in natural product synthesis of dihydro-furan and -pyran formation by ring-closing alkene metathesis

Abstract:
In the last two decades, alkene metathesis has risen in prominence to become a significant synthetic strategy for alkene formation. Many total syntheses of natural products have used this transformation. We review the use, from 2003 to 2015, of ring-closing alkene metathesis (RCM) for the generation of dihydro-furans or -pyrans in natural product synthesis. The strategies used to assemble the RCM precursors and the subsequent use of the newly formed unsaturation will also be highlighted and placed in context.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1039/C6OB00593D

Authors


More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Role:
Author
More from this funder
Funding agency for:
Ribaucourt, A
Grant:
316955
More from this funder
Funding agency for:
Jacques, R
Pal, R
Parker, N
Sear, C
Smith, P
Grant:
EP/L015838/1
EP/L015838/1
EP/L015838/1
EP/L015838/1
EP/L015838/1
Publisher:
Royal Society of Chemistry Publisher's website
Journal:
Organic and Biomolecular Chemistry Journal website
Volume:
14
Issue:
25
Pages:
5875-5893
Publication date:
2016-04-25
Acceptance date:
2016-04-13
DOI:
EISSN:
1477-0539
ISSN:
1477-0520
Pubs id:
pubs:615173
UUID:
uuid:c9ba6bd1-2be1-4ff0-8b8a-800d8e8b640d
Local pid:
pubs:615173
Source identifiers:
615173
Deposit date:
2016-04-13

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