Pathophysiology of severe malaria in children.

Journal article

Over the past decade there has been a growing recognition that the rationalization of severe malaria in children into the two major syndromes of cerebral malaria and severe malaria anaemia is much too simplistic. Indeed, it has become apparent that death from severe malaria may arise from a wider spectrum of pathophysiological disorders with many features in common with the derangements seen in sepsis syndromes. Amongst these derangements acidosis has emerged as a central feature of severe ma...

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Authors: Maitland, K; Marsh, K

• Publication status: Published
• Journal: Acta tropica
• Volume: 90
• Issue: 2
• Pages: 131-140
• Publication date: 2004-04-01
• DOI: 10.1016/j.actatropica.2003.11.010
• EISSN: 1873-6254
• ISSN: 0001-706X
• Language: English
• Keywords: Microcirculation; Humans; Malaria; Respiratory Insufficiency; Coma; Anemia; Acidosis; Africa; Severity of Illness Index; Cytokines; Child