The human oocyte and cumulus cells relationship: new insights from the cumulus cell transcriptome.

Journal article

It is widely recognized that bi-directional communication exists between the human oocyte and cumulus cells (CCs) which is essential for the production of competent oocytes. CCs originate from granulosa cells (GCs) which differentiate into mural GCs and CCs during follicular antrum formation. CCs are biologically distinct from other follicular cells and perform specialized roles, transmitting signals within the ovary and supporting oocyte growth and maturation during the later stages of folli...

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Authors: Huang, Z; Wells, D

• Publication status: Published
• Journal: Molecular human reproduction
• Volume: 16
• Issue: 10
• Pages: 715-725
• Publication date: 2010-10-01
• DOI: 10.1093/molehr/gaq031
• EISSN: 1460-2407
• ISSN: 1360-9947
• Language: English
• Keywords: Female; Humans; Signal Transduction; Oocytes; Gene Expression Profiling; Cumulus Cells