Journal article
Neutralizing antibodies to human immunodeficiency virus type-1 gp120 induce envelope glycoprotein subunit dissociation.
- Abstract:
-
The spectrum of the anti-human immunodeficiency virus (HIV) neutralizing immune response has been analyzed by the production and characterization of monoclonal antibodies (mAbs) to the viral envelope glycoproteins, gp41 and gp120. Little is known, however, about the neutralization mechanism of these antibodies. Here we show that the binding of a group of neutralizing mAbs that react with regions of the gp120 molecule associated with and including the V2 and V3 loops, the C4 domain and support...
Expand abstract
- Publication status:
- Published
Actions
Authors
Bibliographic Details
- Journal:
- Journal of experimental medicine
- Volume:
- 183
- Issue:
- 2
- Pages:
- 473-484
- Publication date:
- 1996-02-01
- DOI:
- EISSN:
-
1540-9538
- ISSN:
-
0022-1007
- Source identifiers:
-
16058
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:16058
- UUID:
-
uuid:c98f2b0c-8d18-4666-afbc-d08631267950
- Local pid:
- pubs:16058
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 1996
If you are the owner of this record, you can report an update to it here: Report update to this record