Journal article
Germline DNA repair gene mutations in young-onset prostate cancer cases in the UK: evidence for a more extensive genetic panel
- Abstract:
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BACKGROUND: Rare germline mutations in DNA repair genes are associated with prostate cancer (PCa) predisposition and prognosis.
OBJECTIVE: To quantify the frequency of germline DNA repair gene mutations in UK PCa cases and controls, in order to more comprehensively evaluate the contribution of individual genes to overall PCa risk and likelihood of aggressive disease.
DESIGN, SETTING, AND PARTICIPANTS: We sequenced 167 DNA rep...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Version of record, pdf, 1012.5KB)
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- Publisher copy:
- 10.1016/j.eururo.2019.01.050
Authors
Funding
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- European Urology Journal website
- Volume:
- 76
- Issue:
- 3
- Pages:
- 329-337
- Publication date:
- 2019-02-15
- Acceptance date:
- 2019-01-31
- DOI:
- EISSN:
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1873-7560
- ISSN:
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0302-2838
- Pmid:
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30777372
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:975961
- UUID:
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uuid:c8c9b7fb-cc1a-4e54-bc95-6c011130bade
- Local pid:
- pubs:975961
- Source identifiers:
-
975961
- Deposit date:
- 2019-06-19
Terms of use
- Copyright holder:
- Leongamornlert et al
- Copyright date:
- 2019
- Notes:
- © 2019 The Authors. Published by Elsevier B.V. on behalf of European Association of Urology under a Creative Commons license.
- Licence:
- CC Attribution (CC BY)
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