Back to Search

Journal article

Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants.

Abstract:: Olefin cross-metathesis (CM)-based protocols enable short, flexible and regiocontrolled access to substituted furan derivatives. Specifically, CM of allylic alcohol and enone components provides γ-hydroxyenone intermediates that are cycloaromatized to the final furan derivatives on exposure to either acid or a discrete Heck arylation step. This latter process concomitantly introduces an extra substituent onto the furan target with complete control of regiochemistry. The methodology described ...
Expand abstract
Collapse abstract

Publication status:: Published

Actions

Email

Email this record

Send the bibliographic details of this record to your email address.

Your Email
Please enter the email address that the record information will be sent to.

-
Your message (optional)
Please add any additional information to be included within the email.
Cite

Cite this record

APA Style

Donohoe, T., Bower, J., & Basutto, J. (2010). Olefin cross-metathesis-based approaches to furans: procedures for the preparation of di- and trisubstituted variants. Nature Protocols, 5(12), 2005–2010.

MLA Style

Donohoe, T., et al. “Olefin Cross-Metathesis-Based Approaches to Furans: Procedures for the Preparation of Di- and Trisubstituted Variants.” Nature Protocols, vol. 5, no. 12, 2010, pp. 2005–10.

Chicago Style

Donohoe, T, J Bower, and J Basutto. 2010. “Olefin Cross-Metathesis-Based Approaches to Furans: Procedures for the Preparation of Di- and Trisubstituted Variants.” Nature Protocols 5 (12): 2005–10.
Tweet
Print

Access Document

Publisher copy:: 10.1038/nprot.2010.147

Authors

+ Donohoe, T More by this author

Institution:

University of Oxford

Division:

MPLS

Department:

Chemistry

Sub department:

Organic Chemistry

Role:

Author

+ Bower, J More by this author

Role:

Author

+ Basutto, J More by this author

Role:

Author

Bibliographic Details

Journal:: Nature protocols
Volume:: 5
Issue:: 12
Pages:: 2005-2010
Publication date:: 2010-12-01
DOI:: 10.1038/nprot.2010.147
EISSN:: 1750-2799
ISSN:: 1754-2189

Item Description

Language:: English
Keywords:: Alkenes

Furans

Molecular Structure
Pubs id:: pubs:103637
UUID:: uuid:c8acb363-ba76-4917-bf70-cf4727441816
Local pid:: pubs:103637
Source identifiers:: 103637
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2010

Licence:: Terms and Conditions of Use for Oxford University Research Archive

Metrics

Views and Downloads

About views and downloads

If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP