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Journal article

CD45 in memory and disease.

Abstract:

CD45 (the leukocyte common antigen) is known to function as a tyrosine phosphatase in leukocyte signaling. Biochemical studies indicate that CD45 is involved in the regulation both of T cell receptor-associated kinases and Janus kinases that transmit signals from cytokine receptors. However, the function of the different isoforms of CD45 generated by complex alternative splicing, and indeed the role of the whole extracellular domain of the molecule, remain mysterious. Analysis of CD45 knock-o...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Archivum immunologiae et therapiae experimentalis
Volume:
50
Issue:
2
Pages:
85-93
Publication date:
2002-01-01
EISSN:
1661-4917
ISSN:
0004-069X
Source identifiers:
32112
Language:
English
Keywords:
Pubs id:
pubs:32112
UUID:
uuid:c89d7632-7085-47ea-bef2-d365cc6e4407
Local pid:
pubs:32112
Deposit date:
2012-12-19

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