Kidney stones: a fetal origins hypothesis.

Journal article

Kidney stones are common, with a multifactorial etiology involving dietary, environmental, and genetic factors. In addition, patients with nephrolithiasis are at greater risk of hypertension, diabetes mellitus, metabolic syndrome, and osteoporosis, although the basis for this is not fully understood. All of these renal stone-associated conditions have also been linked with adverse early-life events, including low-birth weight, and it has been suggested that this developmental effect is due to...

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Authors: Howles, SA; Edwards, M; Cooper, C; Thakker, R

• Publication status: Published
• Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
• Volume: 28
• Issue: 12
• Pages: 2535-2539
• Publication date: 2013-12-01
• DOI: 10.1002/jbmr.1993
• EISSN: 1523-4681
• ISSN: 0884-0431
• Language: English
• Keywords: Hypertension; Kidney Calculi; Risk Factors; Fetus; Models, Biological; Humans; Metabolic Syndrome X; Fetal Development; Diabetes Mellitus, Type 2