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Oxaliplatin as a radiosensitiser for upper and lower gastrointestinal tract malignancies: what have we learned from a decade of translational research?

Abstract:

Some of the greatest advances in the treatment of solid malignancies have resulted from the combination of chemotherapy and radiotherapy treatments. This article comprehensively reviews the current clinical evidence for oxaliplatin-based chemo-radiotherapy that may improve local control and survival. In order to understand how clinical studies should be designed, the pre-clinical evidence for the use of oxaliplatin chemotherapy as a radiosensitising agent is appraised. Particular focus is pla...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Journal:
Critical reviews in oncology/hematology More from this journal
Volume:
83
Issue:
3
Pages:
353-387
Publication date:
2012-09-01
DOI:
EISSN:
1879-0461
ISSN:
1040-8428
Language:
English
Keywords:
Pubs id:
pubs:254251
UUID:
uuid:c87cae97-07af-4b39-a248-7d796381fb9a
Local pid:
pubs:254251
Source identifiers:
254251
Deposit date:
2012-12-19

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