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The SWiFT trial (Study of Whole Blood in Frontline Trauma)—the clinical and cost effectiveness of pre-hospital whole blood versus standard care in patients with life-threatening traumatic haemorrhage: study protocol for a multi-centre randomised controlled trial

Abstract:

Complex cardiac surgery is one of the largest users of blood component stocks with approximately 20 to 40% of patients needing a transfusion during their hospital stay. Transfusion risk is increased further with the use of cardiopulmonary bypass, associated with a multifactorial coagulopathy and increased microvascular bleeding post bypass. Residual anticoagulation and anti-platelet agents in this patient group can also contribute to the haemostatic imbalance. Plasma transfusion is a key trea...

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Publication status:
Published
Peer review status:
Peer reviewed

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Role:
Author
ORCID:
0000-0002-6143-0421
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Role:
Author
ORCID:
0000-0002-5187-1952
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Role:
Author
ORCID:
0000-0001-6823-8937


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Funder identifier:
10.13039/100009033
Grant:
21-102-GEN
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Funder identifier:
10.13039/100009941
Grant:
Letter dated 22 Mar 2021


Publisher:
BioMed Central
Journal:
Trials More from this journal
Volume:
24
Issue:
1
Pages:
725-725
Article number:
725
Publication date:
2023-11-14
DOI:
EISSN:
1745-6215
ISSN:
1745-6215


Language:
English
Keywords:
Pubs id:
1564849
Local pid:
pubs:1564849
Source identifiers:
W4388659851
Deposit date:
2026-06-01
ARK identifier:
This ORA record was generated from metadata provided by an external service. It has not been edited by the ORA Team.

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